p53 ensures the normal behavior and modification of G1/S-specific histone H3.1 in the nucleus
Results Loss of p53 causes the perinuclear accumulation of lysine 27-trimethylated histone H3 (H3K27me3) Using super-resolution three-dimensional structured illumination microscopy (SIM), we found that silencing of TP53 by its siRNAs (siTP53) in normal …