The global scaffold technology market size is calculated at USD 2.66 billion in 2025 and is expected to reach around USD 8.58 billion by 2034, growing at a CAGR of 13.9% from 2024 to 2034.

Ottawa, Nov. 26, 2024 (GLOBE NEWSWIRE) -- The global scaffold technology market size was valued at USD 2.34 billion in 2024 and is predicted to hit around USD 7.53 billion by 2033, a study published by Towards Healthcare a sister firm of Precedence Statistics.

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Scaffold Technology Market: Transforming the Healthcare Industry

Scaffolds provide structural support to cells, allowing for the formation of new tissues. They find applications in tissue engineering and regenerative medicine. Scaffold technology is pivotal in tissue regeneration, which helps to heal and replace obliterated tissues and organs. Tissue repair remains a key issue since the worldwide population continues to age. The increasing occurrence of chronic disorders contributes to market growth. Some chronic diseases, like diabetes, lead to chronic wounds, often requiring scaffolds to heal the wound.

Tissue engineering is rapidly becoming important for improving damaged tissues or organs. Scaffolds play a crucial role in the development of 3D tissue structures. With the rising incidences of severe injuries, the demand for scaffold technology for tissue engineering and wound healing is increasing. Moreover, the increase in the number of surgeries has propelled the growth of the market.

• For instance, according to a report published by the IMDEA Materials Institute in August 2023, over four million bone graft and bone replacement procedures are performed worldwide each year.
  

Major Trends in the Scaffold Technology Market

Need for Regenerative Medicine: The increasing prevalence of chronic diseases and an aging population accentuate the need for regenerative medicine. Older people are more prone to chronic diseases, which may lead to organ failure. Regenerative medicine restores the function and structure of damaged tissues and organs caused by chronic diseases, reducing the burden of chronic disease management. According to the CDC report published in 2024, six in 10 Americans have at least one chronic disease, and four in 10 have two or more chronic diseases, boosting the demand for regenerative medicine.

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Advancements in Material Science: Advancements in material science led to the development of improved scaffold materials, including bioactive ceramics, hydrogels, and biodegradable polymers. Such materials replicate the physical environment outside the cell, which promotes cell growth. The National Institute of Biomedical Imaging and Bioengineering (NIBIB) states that bioactive scaffolds have the potential to greatly enhance the interface between engineered tissue and the body, thus lowering the rejection rates and increasing the effectiveness of the engineered tissue​. In addition, synthetic materials are in high demand due to their effectiveness and high treatment accuracy. FDA also approved synthetic polymers, such as polyethylene glycol (PEG), poly (lactic-co-glycolic acid) (PLGA), polycaprolactone (PCL), and ultra-high molecular weight polyethylene (UHMWPE), that have been incorporated as structural components in tissue engineering scaffolds.

Government Policies and Grants: Support from governments and regulatory authorities is another factor that fuels the growth of the scaffold technology market. For instance, Japan’s Regenerative Medicine Promotion Act promotes regenerative medicine. In the U.S., the Food and Drug Administration is urging the advancement and improvement of regenerative treatments through faster approval processes for scaffold technologies. According to the U.S. Department of Health and Human Services (HHS), governments around the world are expected to spend about USD 6 billion on tissue engineering research by 2025.

Increasing Incidences of Bone and Joint Disorders: A rapid increase in the frequency of bone and joint disorders boosts the adoption of scaffold technologies. According to a report published by the WHO, approximately 1.71 billion people worldwide have musculoskeletal conditions, driving the need for orthopedic implants/regenerative treatments. Orthopedic surgery is one of the most vital areas of application of scaffold technologies for bone healing and tissue regeneration. The rising instances of fractures, osteoarthritis, and osteoporosis further propel the market. According to a report by the U.S. Surgeon General, osteoporotic fractures are common in the U.S., with an estimated 1.5 million suffering from fragility fractures each year.

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Regional Insights

Presence of Leading Players to Maintain North America’s Dominance in the Market

In 2023, North America dominated the scaffold technology market by capturing the largest share, and the region is expected to sustain its dominance in the near future. This is mainly due to the presence of leading market players, such as Thermo Fisher Scientific, Inc., 3D Biotek LLC, and Corning Incorporated, leading to rapid innovations in scaffold technology. Various regulatory agencies in the U.S., including the FDA, are investing in the development of regenerative medicine that benefits the region and positions it as the market leader. Moreover, the rising number of bone replacement surgeries further contributes to regional market growth.

• According to the National Institute of Health (NIH), about 1 million hip and knee replacement procedures are performed each year in the U.S.
  

Asia Pacific is anticipated to be the fastest-growing region during the forecast period. This is mainly due to the rising emphasis on personalized therapeutic approaches. With the rising burden of chronic diseases and surgeries, governments are investing heavily in the research of gene therapy and regenerative medicine. Moreover, the increasing number of organ transplant procedures performed every year contributes to the market growth in Asia Pacific.

• According to the NIH, about 17,000 to 18,000 solid organ transplants are performed every year in India, which is the most in the world after the U.S. and China.
  

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Scaffold Technology Market Segmentation

• By type, the hydrogels segment dominated the market with the largest share in 2023, owing to their high biocompatibility and ability to emulate the natural cellular environment. These scaffolds are applied in wound healing and cartilage regeneration and repair.
• By disease, the orthopedics, musculoskeletal & spine segment led the market in 2023. This is mainly due to a significant rise in the occurrence of bone fractures due to osteoporosis. However, scaffolds can facilitate bone repair. On the other hand, the neurology segment is expected to grow at the fastest rate due to rising investments in scaffold-based neural tissue engineering to develop better treatment options.
• By application, the stem cell therapy, regenerative medicine & tissue engineering segment dominated the global scaffold technology market in 2023. The segment growth is attributed to the rising demand for stem cell therapy and personalized treatments. Tissue engineering plays a crucial role in stem cell therapy, in which scaffolds are extensively used to promote the growth of stem cells.
• By end-use, the biotechnology & pharmaceutical companies segment held the dominating share of the market in 2023 due to the rising investments by these companies in the development of novel drugs and therapeutics. Novel therapeutic approaches often require scaffold technology for tissue engineering, drug testing, and studying cell and organ systems.

Competitive Landscape

The market continues to evolve rapidly, with 2023 witnessing significant advancements and a dynamic competitive landscape. Prominent players operating in the scaffold technology market are Thermo Fisher Scientific, Inc., CytoNest Inc., Pelobiotech, Merck KGaA, 3D Biotek LLC, Tempo Therapeutics, Sanofi, Medtronic, Becton, Dickinson, and Company, Tecan Trading AG, Molecular Matrix, Inc., REPROCELL Inc., 4titude, Akron Biotech, Vericel Corporation, Allergan, Avacta Life Sciences Limited., Corning Incorporated, Matricel GmbH, and NuVasive, Inc. These companies actively participate in the research and development programs to innovate scaffold techniques.

CytoNest Inc. is making efforts to meet the overall demand for scaffolds with its recent launch of CytoSurge 3D fiber scaffold, an innovative product for enhancing tissue engineering and cell production.

Latest Developments in the Scaffold Technology Market

• In July 2024, researchers from the First Affiliated Hospital of Xi'an Jiaotong University introduced a core-shell microfibrous scaffold designed for rotator cuff repair. This advanced scaffold aims to enhance tissue regeneration and healing, providing a more effective solution for patients with rotator cuff injuries.
• In April 2024, Abbott announced that the U.S. Food and Drug Administration (FDA) approved its Esprit BTK Everolimus Eluting Resorbable Scaffold System (Esprit BTK System). This system is designed to treat individuals with chronic limb-threatening ischemia (CLTI) below-the-knee (BTK). The Esprit BTK System offers a significant advancement over traditional balloon angioplasty, as it keeps arteries open and delivers drug to support vessel healing before completely dissolving. This is the first FDA-approved stent or drug-coated balloon for use below the knee in the U.S., providing a novel approach to improving long-term vessel patency.
• In June 2023, RevBio received a USD 2 million grant to advance its novel dental adhesive bone scaffold product. This funding supports the development of next-generation bone scaffolds for dental applications, helping RevBio improve the quality of care for patients with bone defects in dental procedures
• In June 2023, the Indian Drugs Controller approved Cholederm, India’s first animal-derived tissue engineering scaffold. This Class D medical device is designed to aid in healing skin wounds, including burn wounds, diabetic wounds, and myocardial infarction. The approval of Cholederm marks a significant step forward in the development of tissue-engineered scaffolds within India, highlighting the country's growing capabilities in the medical technology sector.

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Segments Covered in the Scaffold Technology Market Report

By Type 

• Hydrogels
• Wound Healing
• 3D Bioprinting
• Immunomodulation
• Nanofiber Based Scaffolds
• Polymeric Scaffolds
• Micropatterned Surface Microplates
  

By Disease

• Orthopedics, Musculoskeletal & Spine
• Neurology
• Cancer
• Skin & Integumentary
• Dental
• Cardiology & Vascular
• Urology
• GI, Gynecology
• Others
  

By Application

• Stem Cell Therapy, Regenerative Medicine & Tissue Engineering
• Drug Discovery
• Others
  

By End-use

• Biotechnology & Pharmaceutical Companies
• Hospitals & Diagnostic Centers
• Research Laboratories & Institutes
• Others

By Region

• North America
• Asia Pacific
• Europe
• Latin America
• Middle East and Africa (MEA)
  

Discover our detailed Table of Contents (TOC) for the Industry, providing a thorough examination of market segments, material, emerging technologies and key trends. Our TOC offers a structured analysis of market dynamics, emerging innovations, and regional dynamics to guide your strategic decisions in this rapidly evolving healthcare field - https://www.towardshealthcare.com/table-of-content/scaffold-technology-market-sizing

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