The market size of endometriosis in the US is estimated to be ~USD 1,200 million in 2022 and is projected to increase by 2032.

LAS VEGAS, NEVADA, UNITED STATES, March 22, 2024 /EINPresswire.com/ -- DelveInsight’s “Endometriosis Market Insights, Epidemiology, and Market Forecast-2032″ report offers an in-depth understanding of the Endometriosis, historical and forecasted epidemiology as well as the Endometriosis market trends in the United States, EU4 (Germany, Spain, Italy, France) the United Kingdom and Japan.

To Know in detail about the Endometriosis market outlook, drug uptake, treatment scenario and epidemiology trends, Click here; Endometriosis Market Forecast

Some of the key facts of the Endometriosis Market Report:

The Endometriosis market size is anticipated to grow with a significant CAGR during the study period (2019-2032).
In January 2022, ObsEva SA released favorable initial findings from the Phase 3 EDELWEISS 3 trial concerning linzagolix, an oral GnRH antagonist, indicating positive outcomes for women experiencing moderate to severe endometriosis-associated pain (EAP).
In February 2022 ObsEva SA revealed a strategic licensing deal with Theramex aiming to facilitate the global market entry and commercialization of linzagolix, excluding the United States, Canada, and Asia. Linzagolix, under development as a prospective remedy for endometriosis-associated pain, recently demonstrated encouraging initial results in its Phase 3 trial (EDELWEISS 3), as announced by ObsEva.
Key Endometriosis Companies: AbbVie, Neurocrine Biosciences, ObsEva, Kissei Pharmaceuticals, SWK, Enteris BioPharma, Bayer, Hope Medicine, Tiumbio, Organon, and others
Key Endometriosis Therapies: linzagolix (ObsEva SA), Ovarest (Enteris Biopharma), HMI-115 (Hope Medicine), Elagolix + estradiol/norethindrone acetate (AbbVie/Neurocrine Biosciences), and others
The total prevalent cases of endometriosis in the US comprised ~9,465,000 in 2022 and are projected to increase by 2032.
The market size of endometriosis in the US is estimated to be ~USD 1,200 million in 2022 and is projected to increase by 2032.
In 2022, the total prevalent cases of endometriosis in the US were ~9,465,000, projected to increase during the forecast period (2023–2032).
In 2022, the total diagnosed prevalent cases of endometriosis in the US were ~4,732,500, projected to increase during the forecast period (2023–2032).
In the US, the most endometriosis-affected people were found in the 18–29 age group, with ~4,993,000 cases in 2022. These cases are estimated to increase by 2032.
The diagnosed prevalent cases of endometriosis by pain severity in the US were ~1,183,100 for mild, ~ 1,893,000 for moderate, and ~1,656,400 for severe in 2022.
As per Delveinsight’s analysis, the total number of treated cases of endometriosis was ~2,839,500 in 2022, projected to increase during the forecast period (2023–2032).
The Endometriosis market is expected to surge due to the disease's increasing prevalence and awareness during the forecast period. Furthermore, launching various multiple-stage Endometriosis pipeline products will significantly revolutionize the Endometriosis market dynamics.
There is no lasting treatment for endometriosis, but available treatment options help in disease management, including surgical and nonsurgical treatments.
Nonsurgical endometriosis includes oral contraceptives, progestin, gonadotropin-releasing hormone antagonists, gonadotropin-releasing hormone agonists, nonsteroidal anti-inflammatory drugs (NSAIDs), and others. Surgical treatment of endometriosis includes laparoscopy, laparotomy, hysterectomy, etc.

Endometriosis Overview

Endometriosis is a chronic condition in which tissue similar to the lining of the uterus grows outside the uterus. This tissue, called endometrial-like tissue, can be found on the ovaries, fallopian tubes, outer surface of the uterus, and other organs within the pelvis. During a woman's menstrual cycle, this tissue responds to hormonal changes, thickening, breaking down, and bleeding. However, unlike the tissue inside the uterus that exits the body during menstruation, the displaced endometrial-like tissue has no way to exit the body. This can lead to inflammation, scar tissue formation, and the development of adhesions, causing pain, infertility, and other complications.

The exact cause of endometriosis is not fully understood, but it is believed to involve a combination of genetic, hormonal, and immune system factors. Common symptoms of endometriosis include pelvic pain, especially during menstruation, pain during intercourse, heavy menstrual periods, infertility, and gastrointestinal issues such as diarrhea, constipation, and bloating.

Diagnosis of endometriosis often involves a combination of medical history, pelvic examinations, imaging tests such as ultrasound or MRI, and minimally invasive procedures like laparoscopy, where a camera is inserted into the abdomen to visualize and potentially biopsy any abnormal tissue.

Treatment options for endometriosis aim to alleviate symptoms and may include pain medications, hormonal therapies such as birth control pills or GnRH agonists to suppress menstruation, surgical removal of endometrial-like tissue (excision), or in severe cases, hysterectomy with removal of the ovaries. Additionally, lifestyle changes, dietary modifications, and alternative therapies like acupuncture or physical therapy may provide relief for some individuals with endometriosis.

Endometriosis is a chronic condition that can significantly impact a person's quality of life, and ongoing management often requires a multidisciplinary approach involving gynecologists, pain specialists, and mental health professionals.

Endometriosis Epidemiology

The epidemiology section provides insights into the historical, current, and forecasted epidemiology trends in the seven major countries (7MM) from 2019 to 2032. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides a detailed analysis of the diagnosed patient pool and future trends.

Endometriosis Epidemiology Segmentation:

The Endometriosis market report proffers epidemiological analysis for the study period 2019–2032 in the 7MM segmented into:
Total Prevalence of Endometriosis
Prevalent Cases of Endometriosis by severity
Gender-specific Prevalence of Endometriosis
Diagnosed Cases of Episodic and Chronic Endometriosis

Download the report to understand which factors are driving Endometriosis epidemiology trends @ Endometriosis Epidemiology Forecast

Endometriosis Drugs Uptake and Pipeline Development Activities

The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Endometriosis market or expected to get launched during the study period. The analysis covers Endometriosis market uptake by drugs, patient uptake by therapies, and sales of each drug.
Moreover, the therapeutics assessment section helps understand the drugs with the most rapid uptake and the reasons behind the maximal use of the drugs. Additionally, it compares the drugs based on market share.

The report also covers the Endometriosis Pipeline Development Activities. It provides valuable insights about different therapeutic candidates in various stages and the key companies involved in developing targeted therapeutics. It also analyzes recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.

Endometriosis Therapies

linzagolix (ObsEva SA)
Ovarest (Enteris Biopharma)
HMI-115 (Hope Medicine)
Elagolix + estradiol/norethindrone acetate (AbbVie/Neurocrine Biosciences)

Endometriosis Key Companies

AbbVie
Neurocrine Biosciences
ObsEva
Kissei Pharmaceuticals
SWK
Enteris BioPharma
Bayer
Hope Medicine
Tiumbio
Organon

Discover more about therapies set to grab major Endometriosis market share @ Endometriosis Treatment Landscape

Endometriosis Treatment Market

Endometriosis is currently managed through surgical removal of endometrial lesions via laparoscopy, which helps alleviate pain and improve fertility rates, along with therapeutic approaches aimed at suppressing pain, ovarian function, and estrogen activity. Available pharmacological treatments include oral contraceptives (used off-label), progestins as the primary pharmacological option, and GnRH agonists/antagonists as secondary treatments for endometriosis. However, the latter can induce hypoestrogenism and lead to significant side effects such as drug-induced menopause and osteoporosis.

These treatments for endometriosis, crucially, also affect fertility. Persistent pain, a prevalent and debilitating symptom of the condition, is often managed with NSAIDs, although their effectiveness varies, and prolonged use can result in serious side effects. There is a pressing need in clinical practice for new non-hormonal treatments for endometriosis.

ORILISSA (elagolix) stands as the first FDA-approved oral medication specifically designed to address moderate-to-severe endometriosis pain. ORILISSA is available in two oral doses: 150 mg once daily and 200 mg twice daily. The 150 mg tablets are light pink, oblong, film-coated tablets imprinted with "EL 150" on one side. Additionally, MYFEMBREE (relugolix, estradiol, and norethindrone acetate) is an oral tablet taken once daily. It comprises relugolix, which suppresses estrogen production; estradiol to potentially mitigate bone loss risk; and norethindrone acetate to counteract the effects of estrogen in individuals with uteruses. MYFEMBREE received FDA approval in August 2022.

Scope of the Endometriosis Market Report

Study Period: 2019–2032
Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan]
Key Endometriosis Companies: AbbVie, Neurocrine Biosciences, ObsEva, Kissei Pharmaceuticals, SWK, Enteris BioPharma, Bayer, Hope Medicine, Tiumbio, Organon, and others
Key Endometriosis Therapies: linzagolix (ObsEva SA), Ovarest (Enteris Biopharma), HMI-115 (Hope Medicine), Elagolix + estradiol/norethindrone acetate (AbbVie/Neurocrine Biosciences), and others
Endometriosis Therapeutic Assessment: Endometriosis current marketed and Endometriosis emerging therapies
Endometriosis Market Dynamics: Endometriosis market drivers and Endometriosis market barriers
Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter’s five forces, BCG Matrix, Market entry strategies
Endometriosis Unmet Needs, KOL’s views, Analyst’s views, Endometriosis Market Access and Reimbursement

Table of Contents

1. Endometriosis Market Report Introduction
2. Executive Summary for Endometriosis
3. SWOT analysis of Endometriosis
4. Endometriosis Patient Share (%) Overview at a Glance
5. Endometriosis Market Overview at a Glance
6. Endometriosis Disease Background and Overview
7. Endometriosis Epidemiology and Patient Population
8. Country-Specific Patient Population of Endometriosis
9. Endometriosis Current Treatment and Medical Practices
10. Endometriosis Unmet Needs
11. Endometriosis Emerging Therapies
12. Endometriosis Market Outlook
13. Country-Wise Endometriosis Market Analysis (2019–2032)
14. Endometriosis Market Access and Reimbursement of Therapies
15. Endometriosis Market Drivers
16. Endometriosis Market Barriers
17. Endometriosis Appendix
18. Endometriosis Report Methodology
19. DelveInsight Capabilities
20. Disclaimer
21. About DelveInsight

Related Reports:

Endometriosis Pipeline

"Endometriosis Pipeline Insight, 2024" report by DelveInsight outlines comprehensive insights of present clinical development scenarios and growth prospects across the Endometriosis market. A detailed picture of the Endometriosis pipeline landscape is provided, which includes the disease overview and Endometriosis treatment guidelines.

Endometriosis Epidemiology

DelveInsight's 'Endometriosis Epidemiology Forecast to 2032' report delivers an in-depth understanding of the disease, historical and forecasted Endometriosis epidemiology in the 7MM, i.e., the United States, EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan.

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