The global estrogen receptor agonist market is anticipated to grow at a CAGR of 15.76% over the forecast period (2022 – 2030).

PUNE, MAHARASHTRA, INDIA, March 30, 2022 /EINPresswire.com/ -- Selective Estrogen Receptor Agonist to Hold Largest Market Share in 2021

According to Absolute Markets Insights report, selective estrogen receptor agonist accounted for the highest market share in 2021 and is projected to maintain its dominance over the forecast period (2022-2030) in the estrogen receptor agonist market as they act in organ/tissue specific fashion and avoid adverse, off-target effects. They are majorly used for the treatment of breast cancer, the prevention of osteoporosis, and the maintenance of beneficial serum lipid profiles in postmenopausal women. The increasing burden of chronic disease globally have resulted in the rising drug discovery and development activities by engaging computational tools and bioinformatics methodologies, thereby driving the development of selective estrogen receptor agonist drugs. For instance, Sanofi is developing amcenestrant, which has shown early signs of clinical efficacy in the phase 1/2 AMEERA-1 trial in postmenopausal women with heavily pretreated ER-positive, HER2-negative advanced or metastatic breast cancer. AMEERA-1 is evaluating amcenestrant as monotherapy and in combination with other anticancer therapies. Furthermore, the increasing funding for drug development is impelling the growth of selective estrogen receptor agonist segment. For instance, in July 2020, Olema Oncology received funding of USD 54 million to advance the breast cancer program OP-1250 into phase I/II clinical development and expand ongoing research and development activities in other cancers affecting women. Also, the increasing collaboration activities are anticipated to boost the segment growth. For instance, in July 2020, Zentalis Pharmaceuticals, Inc. a clinical-stage biopharmaceutical company focused on discovering and developing small molecule therapeutics targeting fundamental biological pathways of cancers, announced a clinical collaboration agreement with Eli Lilly and Company in which Zentalis will evaluate the combination of ZN-c5, the Company’s oral selective estrogen receptor degrader (SERD) product candidate, and Verzenio (abemaciclib), Lilly’s CDK4 and 6 inhibitor, in patients with ER+/HER2- advanced breast cancer.

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Key Findings – Global Estrogen Receptor Agonist Market
• In terms of revenue, the global estrogen receptor agonist market is anticipated to grow at a CAGR of 15.76% over the forecast period (2022 – 2030).
• By clinical indication, the cardiovascular health segment will be the fastest growing segment owing to the increasing incidence of CVDs across the globe. As per WHO, an estimated 17.9 million people died from CVDs in 2019. Also, the estrogen receptor agonist are proven efficient to treat CVDs, thereby impelling the segment growth.
• By route of administration, oral segment holds the largest market share in estrogen receptor agonist market owing to its cost efficiency and convenience. Also, they can be rapidly absorbed, thereby mostly preferred. For instance, raloxifene is rapidly absorbed after oral administration, and its absolute bioavailability is 2 %
• By distribution channel, the offline segment registered for the largest market revenue in 2021 and is anticipated to witness the fastest growth rate owing to the increasing number of pharmacies attached to hospitals. Also, the increasing demand for prescription drug is driving the segment growth. In 2021, the prescription drug revenue was estimated about USD 1,031 billion.
• By region, Asia-Pacific region is anticipated to witness the fastest growth over a forecast period owing to the increasing government initiatives and collaboration for the drug development.

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Competitor Insights:
The key companies profiled in the global estrogen receptor agonist market are mentioned below:
• AstraZeneca
• Eli Lilly and Company
• ESTRIGENIX
• Karo Pharma AB
• Merck KGaA
• Oasmia Pharmaceutical AB
• Oncternal Therapeutics.
• Pfizer Inc.
• Tocris Bioscience
• Tokyo Chemical Industry Co., Ltd
• Other Market Participants

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Global Estrogen Receptor Agonist Market
By Product Type
• Endogenous Estrogen Receptor Agonist
• Selective Estrogen Receptor Agonist
• Others

By Clinical Indication
• Breast Cancer
• Fertility
• PCOS
• Osteoporosis
• Neurodegenerative Disorders (Including Multiple sclerosis (MS))
• Inflammatory Diseases
• Cardiovascular Health
• Others

By Route of Administration
• Oral
• Parenteral

By Distribution Channel
• Online
• Offline

By Region
• North America (U.S., Canada, Mexico, Rest of North America)
• Europe (France, The UK, Spain, Germany, Italy, Nordic Countries, Benelux Union, Rest of Europe)
• Asia Pacific (China, Japan, India, New Zealand, Australia, South Korea, Southeast Asia, Rest of Asia Pacific)
• Middle East and Africa (Saudi Arabia, UAE, Egypt, Kuwait, South Africa, Rest of Middle East & Africa)
• Latin America (Brazil, Argentina, Rest of Latin America)

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